Educational dose math only — not medical advice, not a product recommendation, and not a pass/fail on whether a supplement will work for you.
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Nine RCTs, 200–1000 µg/day chromium picolinate, 8–24 weeks. Body weight MD −1.1 kg (95% CI −1.7 to −0.4). Low-quality GRADE; debatable clinical relevance; no dose gradient.

Educational only — not medical advice. Disclaimer.

NIH DSLD market slice

Median200 mcg
Products138
Below76%

Bulk CSV dump 16 January 2026 · label entries through 2025. Disclosed amounts only — proprietary blends without gram weights excluded.

Trial floors

Primary

Cochrane weight review (pooled doses) · 1,000 mcg over 12-16 weeks (limited evidence) · Significant, low-quality evidence — Nine RCTs, 200–1000 µg/day chromium picolinate, 8–24 weeks. Body weight MD −1.1 kg (95% CI −1.7 to −0.4). Low-quality GRADE; debatable clinical relevance; no dose gradient.

Secondary

Pittler 2003 sensitivity analysis · 1,000 mcg over 12-16 weeks (limited evidence) · Primary endpoint missed — Removing one influential trial: −0.9 kg (95% CI −2.0 to 0.2), not statistically significant. Funnel plot asymmetry suggests publication bias.

Label reading notes

  • Picolinate is not interchangeable with chromium polynicotinate or generic chromium on labels.
  • Cochrane rated evidence low-quality; shelf math does not mean clinically meaningful weight loss.
  • Does not address H1-driven appetite from mirtazapine; metabolic lever only.
  • Stay within the 200–1000 µg/day studied range; case reports of renal issues at very high chronic doses.