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2 g/day of branded Magtein in adults aged 18-45 reporting unsatisfying sleep. Overall cognition improved (NIH Total Cognition Composite, p = 0.043) along with reaction time, resting heart rate and HRV. Raven's matrices did not change, and neither did objective sleep from a wearable — only self-reported sleep-related impairment.
Educational only — not medical advice. Disclaimer.
Want the outcome before the arithmetic? The reason check opens any registry entry on this page with its trial result first, then compares your daily intake with the studied amount.
NIH DSLD market slice
Bulk CSV dump 16 January 2026 · label entries through 2025. Disclosed amounts only — proprietary blends without gram weights excluded.
Trial floors
Primary
Cognition and sleep trial (compound weight) · 2,000 mg over 6 weeks · Secondary outcomes only — 2 g/day of branded Magtein in adults aged 18-45 reporting unsatisfying sleep. Overall cognition improved (NIH Total Cognition Composite, p = 0.043) along with reaction time, resting heart rate and HRV. Raven's matrices did not change, and neither did objective sleep from a wearable — only self-reported sleep-related impairment.
Label reading notes
- This dose is compound weight, not elemental magnesium. 2000 mg of magnesium L-threonate carries roughly 144 mg of elemental magnesium — about a third of the daily value, not a large dose.
- Compare it against the elemental magnesium entry before deciding you are covered: a big number on a threonate label is not a big magnesium dose.
- The trial used the branded Magtein preparation. Generic magnesium L-threonate at the same milligram count has no separate trial.
- Cognitive endpoints were mixed — one composite met significance, one reasoning test did not, and objective sleep did not move.